Mutations in NPC1 cause Niemann-Pick Type C. Mice lacking NPC1 only in microglia have rampant neuroinflammation and impaired ...

Objective Juvenile SLE (jSLE) is an autoimmune disease characterised by the presence of high levels of autoantibodies, ...

Despite recent therapeutic breakthroughs, cancer patients continue to face high recurrence and mortality rates due to treatment resistance. Cancer stem cells (CSCs), a subpopulation with self-renewal ...

Reproductive health is fundamentally connected with overall health. The Bia-Echo Asia Centre for Reproductive Longevity and Equality discusses an innovative approach to healthy longevity that is ...

After hours: January 7 at 4:04:26 PM EST Loading Chart for SVRA ...

Scientists mapped how aging alters gene expression across brain cell types in mice, revealing immune activation, neuronal ...

Dec. 3, 2024 — An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to the bacterium that causes the human disease tuberculosis. The ...

This manuscript offers valuable insights by identifying two distinct liver cancer subtypes through multi-omics integration and developing a robust prognostic model, validated across various datasets, ...

Explore how inhibiting myostatin can promote muscle mass in men, addressing sarcopenia, GLP-1 medication effects, and aging ...

Now that we’ve explored the science behind the nutritional and health benefits of mushrooms, let’s put them to use in a simple, wholesome recipe that is both ...

吸烟对心血管健康的有害影响，特别是动脉粥样硬化和血栓形成，已经得到了很好的证实，更详细的机制也在不断出现。作为吸烟不良影响的基本病理生理学，内皮功能障碍、炎症和血栓形成被认为尤为重要。香烟烟雾诱导内皮功能障碍，导致血管扩张和止血调节受损。导致内皮功能障碍的因素包括一氧化氮生物利用度降低、超氧阴离子水平升高和内皮素释放。血管壁的慢性炎症是吸烟诱导动脉粥样硬化的核心发病机制。吸烟会全身性升高炎症标志物 ...

What is Known About the Estrogen Deficiency of Menopause & Specific Autoimmune Diseases It is known that many natural, pathological and therapeutic conditions can change serum estrogen levels ...