DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

On the battleground of the human body, microbes use every skill to mask, infiltrate, manipulate, and evade the immune radar.

Methods: Nasopharyngeal Carcinoma tissues from 3 patients and non-cancerous nasopharyngeal tissues from 3 individuals, all from Fujian Cancer Hospital, were sequenced for m6A methylation. These were ...

They have deployed a bacteria to help them achieve this. Professor Debasish Das and Dr Krishna Kalyani Sahoo of the Department of Biosciences and Bioengineering, IIT Guwahati, have developed an ...

Yoshiki Ochiai, the paper's first author and Ph.D. student in the Protein Engineering and Evolution Unit, tried to improve RNA methylation activity of a bacterial non-site-specific DNA ...

Like bacteria, viruses can cause disease. But unlike bacteria, viral pathogens are not technically living cells. They can only replicate inside another organism, meaning they need a host. These germs ...

They compared data from stool samples collected from coffee drinkers and non-drinkers to identify differences in their gut bacteria ... abundance of all microbial DNA in a sample.

A heterochromatin-dependent transcription machinery connects several proteins required for programmed DNA elimination in Paramecium, elucidating the molecular mechanisms underlying PRC2-dependent ...

Bacteria are known to develop antibiotic resistance in different ways, including mutations in their DNA. Another common mechanism is their ability to actively pump and transport antibiotics out of ...

It started with a finger bone found in a cave in the Altai mountains in Siberia in the late 2000s. Thanks to advances in DNA analysis, this was all that was required for scientists to be able to ...