Pain management can be challenging, but medications can help. The following examines studies that reviewed the efficacy (effectiveness) of naltrexone for pain management. Data from clinical trials ...

A literature search identified more than a dozen published reports on the use of pure opioid antagonists (naloxone, naltrexone, methylnaltrexone) for the management of OIP in pediatric and adult ...

Naltrexone is relatively well tolerated ... [25] Adverse reactions at the injection site include pain, tenderness and swelling, especially in the event of inadvertent subcutaneous injection.