The regulator HIF1α functions in a cancer-microenvironment that lacks oxygen, and it may be involved in resistance to immune checkpoint blockade therapy. In a study published in Nature Communications, ...

induction in T cells. “Intriguingly, under normal oxygen levels in the body, called normoxia, IFN-g induction and glycolysis in T cells are not mediated by HIF1a, a primary regulator of glycolysis, ...

The High Court asked the aviation regulator to investigate whether the supply of oxygen in the long-haul Boeing 777-200LR ...