A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.
The specificity of cranial motor neuron projections is governed by rostrocaudal and dorsoventral patterning mechanisms that produce a diversity of motor neuron subpopulations with distinct ...
He has been actively involved in computational neuroscience research and his simulation model of the subthalamic nucleus projection neuron is recognised as a standard. He he has taught neuroscience ...
F RUIT FLIES are smart. For a start—the clue is in the name—they can fly. They can also flirt; fight; form complex, long-term ...
They found that cGMP in spiny projection neurons was degraded by an ... triggered by nitric oxide was blocked in parts of the neuron that were actively processing information, in contrast to ...
Salk Institute's START technology maps brain connections with unrivaled precision, revealing unique patterns in inhibitory ...
Shown are the three main neuron types in the lateral horn of the vinegar fly Drosophila melanogaster: inhibitory projection neurons (green) respond to attractive odors; third-order neurons of the ...
An example Sst Chordl cell (left) shows dense projections to cortical layer 6, while another inhibitory subtype, Sst Hpse Cbln4 (right), shows dense projections to layer 4.
This three-neuron loop, in which the cerebellum takes center stage ... for the first time, the long-range direct afferent projections from the cerebellar nuclear neurons to amygdala neurons at the ...
Anti-brain aging to increase healthy lifespan: Our long-term goal is to identify molecular and cellular mechanisms that contribute to brain aging, including glia-neuron interactions, systemic ...
Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.