The ribosome is a large assembly of proteins and ribosomal RNAs (rRNAs) that functions to translate messenger RNAs (mRNAs) into proteins. The ribosome catalyzes the assembly of amino acids into ...
The TMs of Sec63 interact with all three subunits of the Sec61p complex. The Brl domain interacts with the Sec61α TM6/7 and TM8/9 loops; it also provides a platform on which the cytosolic domains of ...
Clindamycin, lincomycin Lincosamides Bind to the 50S subunit of the ribosome (PTC), inhibiting ... of mycolyl–arabinogalactan–peptidoglycan complex in the cell wall, thus increasing cell ...
Formyl-methionyl-tRNA is bound to ribosomes by single stranded circular DNA of the phage fd. Addition of neomycin B to this complex permits direct translation of this DNA into protein, which ...
Single-molecule multi-colour fluorescence microscopy allowed the Duss Group at EMBL Heidelberg to capture a movie showing interactions between bacterial RNA polymerase (labelled with the pink sphere) ...
An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.
"Our working hypothesis is that by inserting one of its own proteins into the ribosome, the virus alters ... "This discovery reveals new details about the complex ways viruses in the ocean ...