Nissen and colleagues investigated whether treatment with one such CB1 antagonist, rimonabant, could slow the progression of coronary atherosclerosis in obese patients with the metabolic syndrome.
Curioni C and André C (2006) Rimonabant for overweight or obesity. The Cochrane Database of Systematic Reviews, Issue 4, Art. No CD006162.pub2 Rimonabant is the only drug currently under ...
The RIO-Diabetes study, which was performed in 159 centers in 11 countries, showed that rimonabant 20 mg once daily can reduce body weight and improve cardiovascular and metabolic risk factors in ...
The results from the study showed that the patients taking the higher dose of rimonabant lost more weight after one year than those who had taken a placebo. As in the animal studies, rimonabant ...
Skye launched its Phase 2 trial of nimacimab in obesity in August 2024. This trial, which is the first to also assess a GLP-1/CB1 inhibitor combination, is expected to report interim weight loss data ...