A new paper from Elham Azizi's lab and collaborators has been accepted for publication in Genome Research, marking a ...
ScRNA-seq Analysis Copilot serves as an interactive agent to learn single cell sequencing, answering questions and helping new learners to practice analysis.
单核细胞来源的肿瘤相关巨噬细胞 (Mo-TAM) 强烈浸润弥漫性神经胶质瘤,具有显着的异质性。使用单细胞转录组学,我们绘制了 51 名异柠檬酸脱氢酶 (IDH) 野生型胶质母细胞瘤或 IDH 突变胶质瘤患者的 Mo-TAMs ...
To visualize the cell clusters, there are a few different dimensionality reduction techniques that can be helpful. The most popular methods include t-distributed stochastic neighbor embedding (t-SNE) ...
【导读】转移级联反应是一个多方面且高度侵袭的过程,是导致死亡的主要原因。在转移过程中,循环系统中静止癌细胞的存活至关重要,但由于缺乏普遍接受的静止癌症模型,科学界的理解受到限制。2024年10月11日,北京大学肿瘤医院、苏州大学肿瘤研究所詹启敏院士团 ...
超过50%的患者有5年的总生存期 。然而,MM在现阶段仍然是一种难以治愈的疾病。 单细胞RNA测序(scRNA-seq)技术是一项革命性的技术,使科学家能够更好地了解肿瘤和微环境之间的差异 。目前,它已应用于各种血癌,包括白血病、多发性骨髓瘤、骨髓增生异常 ...
Prenatal skin atlas and hair-growing skin organoids could inform on new approaches to enable scarless wound healing or ...
发表在《细胞》杂志上的一项新研究挑战了单细胞数据集不会有隐私泄露风险的假设。 获取公开可用的人类单细胞基因表达数据集或scRNA-seq数据集,大大增强了研究人员对复杂生物系统和各种疾病词源的理解。然而,可获得性的增加引起了人们对捐赠细胞的个人隐私的更大关注,以及他们的私人健康细节在未经同意的情况下被分享的可能性。 先前对这些隐私泄露的研究主要集中在大量基因表达数据共享上,其中基因的平均表达水平是 ...
A research team from Beihang University and Tsinghua University has demonstrated that integrating learnable neural units with ...
Data are available in a public, open access repository. Data are available on reasonable request. All sequencing scRNA-seq data are publicly available via the NCBI Gene Expression Omnibus (GEO) using ...