Muscle stem cells are adult stem cells, present in skeletal muscle tissue, which can self-renew and are capable of giving rise to skeletal muscle cells. These stem cells are activated in response ...

Decision letter after peer review: Thank you for submitting your article "Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies" for consideration by eLife. Your ...

Background: It is well established that prolonged, exhaustive endurance exercise is capable of inducing skeletal muscle damage and temporary impairment of muscle function. Although skeletal muscle has ...

Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL. (P.Z., A.W.T.S., N.X.H., E.M.P., C.B.P ...

Cornell University researchers have created a detailed understanding of how muscles lose their ability to regenerate as they age, using mice as a model ... between cell types and how they induce ...

Knowing the precise mechanisms by which MYC drives muscle growth could prove ... the levels of MYC in their skeletal muscles using a specialized mouse model. The mice weren't given an exercise ...

The researchers used a mouse model ... heart cells was also reduced. The heart’s pumping ability and how well the heart relaxes and fills with blood between beats were unaffected, suggesting that ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Researchers at Imperial College London have discovered that specialist macrophages—a type of white blood cell—play a key role in the control of muscle contraction and locomotion. The discovery ...

Bone regeneration is mediated by the action of resident skeletal stem/progenitor cells (SSPCs) from periosteum and bone marrow, and SSPCs from skeletal muscle adjacent to the fracture site 1–4. SSPCs ...