Based on a protein’s three-dimensional surface structure, the algorithm designs molecules that bind specifically to the protein according to the lock- and-key principle, so they can interact ...
The Structural and Functional Diversity of Peptides Studies suggest that peptides may exhibit remarkable diversity in structure and function, which arises from variations in amino acid composition, ...
The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins ... Now, AlphaFold 3 has widened the reach of the ...
The triaxial structure that we obtain can provide important constraints on the Sagittarius progenitor, as well as the central dark matter distribution under the assumption of dynamical equilibrium.
In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide targeting ?-catenin, a historically "undruggable" protein, in just two months. This ...