Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

CHARALAMPOUS and Hegsted 1 found that metabolic acetylation is impaired in experimental diabetes. They demonstrated this in alloxan-diabetic rats by the measurement of acetylated paraaminobenzoic ...

Post-translational modifications (PTMs) of α-synuclein (α-syn) such as acetylation and phosphorylation play important yet distinct roles in regulating α-syn conformation, membrane binding, and amyloid ...

The findings demonstrate the essential contribution of the microtubule network to changes in cell shape driven by mechanical forces. Furthermore, we observed a flow-dependent increase in microtubule ...

The pathophysiological mechanisms regulating YAP subcellular localization after myocardial infarction remain poorly defined. We identified YAP acetylation at site K265 by in vitro acetylation followed ...

Keywords: human GI tract, gut microbiome, host genetics, host epigenetics, epi-transcriptomics, GI homeostasis, microbiome-derived metabolites, DNA methylation, histone acetylation Important Note: All ...

Dynamic histone modification signatures coordinate developmental programs in strawberry fruit ripening The authors declare ...

The National Cancer Institute awarded Dr. Courtney Thomas a grant for prostate cancer research focusing on calreticulin's ...

Kim, J. and Sadiora, K. (2024) Systematic Analysis of Post-Translational Modifications for Increased Longevity of ...