引言细胞命运的转换是现代生命科学和医学领域中最具革命性的话题之一。通过精准操控细胞命运,研究人员可以将一种成熟的细胞类型重编程为另一种完全不同的细胞类型,这种过程不仅揭示了生命系统的可塑性,更为再生医学、疾病建模和个性化治疗开辟了新的可能性。然而,重 ...
We help investigators generate induced pluripotent stem cells from human skin fibroblasts using lentiviral vectors delivering five reprogramming factors (Oct4, Sox2, Klf4, c-Myc and Nanog). The end ...
IHC staining for the stem cell reprogramming factors Oct4, Nanog, Myc, Klf4, and Sox2 was performed in the vascular tumor samples as well as the two control tissue sets. Representative images of ...
This manuscript presents a careful study of nervous system regeneration in the larval sea star using new transgenic tools for marking and following cells involved in regeneration. The authors find ...