More than 1,000 different drugs are thought to cause liver damage and one French study estimated the global annual incidence rate of drug-related liver damage as 8 cases per 100,000 inhabitants ...
The adverse events from TMZ therapy are often haematologic. Nonetheless, there are rare instances of clinically significant cholestatic liver injury.1 2 There have been reported cases of LEV-induced ...
The company’s lead product is Livmarli (maralixibat), an orally administered ileal bile acid transporter (“IBAT”) inhibitor approved for the treatment of cholestatic pruritus in patients ...
It is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the U.S. (three months and older), in Europe (two months and older), and in other regions globally.