The Company also announced the discontinuation of the development of its drug INCB000547 for patients with cholestatic pruritus (CP). Both of these drugs stem from Incyte's $750 million acquisition of ...
Linerixibat is a small molecule commercialized by GSK, with a leading Phase III program in Pruritus. According to Globaldata, it is involved in 15 clinical trials, of which 12 were completed, and 3 ...
It is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the U.S. (three months and older), in Europe (two months and older), and in other regions globally.
The company’s lead product is Livmarli (maralixibat), an orally administered ileal bile acid transporter (“IBAT”) inhibitor approved for the treatment of cholestatic pruritus in patients ...
Cholestasis is characterized by the accumulation of bile acids (BAs) in the liver and is often associated with severe itching (cholestatic pruritus (CP)). Activation of the GPCR hX4 in dorsal root ...
British drugmaker GSK said on Tuesday its experimental therapy, linerixibat, met its main goal in a late-stage trial to treat patients with a so-called relentless itch associated with a rare ...