It is a survival and proliferation factor for a variety of tumor types. EGFR signals through the RAS/RAF/MEK/ERK pathway. Upon activation by extracellular ligands, EGFR dimerizes and ...
LACTB是一种哺乳动物蛋白,其结构域序列与青霉素结合蛋白和β-内酰胺酶相似。最近的一项研究表明,在乳腺癌中,LACTB作为肿瘤抑制因子,参与调节脂质代谢。此后,更多学者对LACTB蛋白进行了探索,报道其在乳腺癌、肝细胞癌、结直肠癌、胶质母细胞瘤等多 ...
【导读】尽管存在表皮生长因子受体酪氨酸激酶抑制剂(EGFR-TKI)等靶向治疗,但由于耐药性阻碍了其疗效,非小细胞肺癌(NSCLC)仍然是一个临床挑战。2024年9月25日,中山大学药学院(深圳)陈洪中团队在期刊《Science ...
The last time an Uzbek president faced a serious challenger was in 1991. Erk hasn’t been allowed to front a candidate since. The Erk (Freedom) Party says it will nominate a candidate to run in ...
Qinzhizhudan formula dampens inflammation in microglia polarization of vascular dementia rats by blocking MyD88/NF-κB signaling pathway: Through integrating network pharmacology and experimental ...
Then, IL-2 signaling is transduced through three distinct pathways: JAK-STAT, MAPK/ERK and PI3K/Akt/mTOR. Recent studies have identified that the IL-2/IL-2R signaling pathway is an essential ...