This useful study examines the function of the rnc gene, which encodes the RNase III ribonuclease, as it relates to virulence of Salmonella Enteritidis. The authors demonstrate that the rnc gene is ...

The vaccine, which is based on the ChAd3 simian adenoviral platform, achieved promising results in a Phase I clinical trial.

Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double strand break can result in insertion or deletion mutations, while repair pathways can be ...

NeuroSense Therapeutics Ltd. ("NeuroSense"), a late-clinical stage biotechnology company developing novel treatments for severe neurodegenerative diseases, today announced transformative findings from ...

CAP-dependent endonuclease (CEN), intended for use across a broad range of flu viruses. Developed by Traws Pharma, Inc. (NASDAQ: TRAW), tivoxavir marboxil (tivoxavir) showed positive topline Phase ...

In this issue of BioTechniques, we present a novel buffer for the long-term preservation of DNA in biological material at room temperature, a colorimetric technique for detecting miRNA, and a review ...

Flap endonuclease-1 (FEN-1), a structure specific nuclease, is an essential enzyme for eukaryotic DNA replication and repair. The crystal structure of FEN-1 from Methanococcus jannaschii ...

A metallo β-lactamase (MBL) fold enzyme, cleavage and polyadenylation specificity factor 73 (CPSF73), is proposed to be the sole endonuclease responsible for 3' end processing of both mRNA classes. We ...