Researchers discovered that the mRNA modification m6A triggers rapid degradation, regulating protein production. This ...

mRNA技术的发展因新冠疫情爆发而加速，也随着新冠疫苗需求的快速消失而陷入瓶颈期。 mRNA领先企业Moderna旗下两款呼吸道合胞病毒（RSV）疫苗的临床 ...

Breakthrough infections, where individuals contract the disease despite vaccination, became a critical issue as variant viruses spread during the pandemic.

It couples the degradation of an mRNA directly to the proteins produced and is significantly faster and more efficient than previously known mechanisms for mRNA degradation. Crucially, this ...

Long before mRNA vaccines captured global attention during the COVID-19 pandemic, researchers were already exploring their ...

The Russian mRNA vaccine under development can be “personalised” based on the genetic analysis of each person’s tumour to ...

In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...

Russia’s mRNA cancer vaccine, launching in 2025, uses AI to personalise treatment, training the immune system to target ...

"Our LNP was able to deliver an mRNA therapeutic that reduced maternal ... as well as understanding the mechanisms of how it gets to the placenta, a question still not fully answered.