随着生物科技的飞速发展,科学家们在抗衰老领域取得了突破性进展,尤其是通过清除‘僵尸细胞’,衰老干预已成为该领域的前沿策略。这类细胞不仅停止分裂,还会释放有害物质,影响周围健康细胞的功能,与多种衰老相关疾病如癌症、痴呆和心血管疾病等紧密相连。
For the first time, a molecular mechanism is identified, for experimental acceleration and deceleration (rejuvenation) of sperm epigenetic aging.
Notably, the emergence of SMC-derived luminal myofibroblasts—in both mice and patients with KD, Takayasu’s arteritis and Giant Cell arteritis—coincided with activation of the mechanistic target of ...
Long-term, low-dose cannabis treatment has been shown to reverse brain aging and enhance cognitive abilities in mice by ...
Mitigating inflammation, inhibiting immunosenescence, and eliminating senescent cells could be promising strategies for enhancing vaccine responses in older people. The mTOR signalling pathway greatly ...
Recently, it was shown that MSU crystals can induce mechanistic target of rapamycin (mTOR) signalling in monocytes encountering these crystals in vitro. The mTOR pathway is strongly implicated in ...