These increases were associated with chromatin remodelling, as an increase in histone H3 Lys4 (H3K4) methylation at GABAergic gene loci was also observed over this period of development.

Research published in Nature Ecology & Evolution introduces a novel method for inferring DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human ...

This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...

beds.ac.uk Background Epigenetics is the study of processes—beyond DNA sequence alteration—producing heritable characteristics. For example, DNA methylation modifies gene expression without altering ...

The Technion-Israel Institute of Technology will award the Harvey Prize in Science and Technology to Prof. Stephen Baylin, Prof. Peter Jones, and Prof. Andrew Feinberg for their groundbreaking work in ...

Researchers analyze various aspects of gene regulation, among which are the three-dimensional structure of the genome and DNA methylation, which differ for different cell types and play significant ...

Liver diseases represent a significant global health challenge, encompassing a spectrum of conditions such as hepatitis, fatty liver disease, cirrhosis, and hepatocellular carcinoma. Recent ...

Hypertrophic cardiomyopathy (HCM) is a prevalent inherited cardiac disease marked by left ventricular hypertrophy, often due ...

Maintaining good cardiovascular health may affect a key process in how cells age, allowing people who are genetically ...