: chemical structures of the nitroimidazoles: benznidazole (8), megazol (9) and a metronidazole analog (10). Several nitroimidazoles possess good oral therapeutic activity against protozoal parasites; ...

In this work, the authors propose that astrocytic aquaporin 4 (AQP4) is the main pathway for tonic water efflux, without which astrocytes undergo cell swelling. These findings are important, because ...