Pyrimidine dimer - Wikipedia
网页Pyrimidine dimers encompass several types, each with distinct structures and implications for DNA integrity. Cyclobutane pyrimidine dimer (CPD) is a dimer which features a four-membered ring formed by the fusion of two double …
Pyrimidine Dimer - an overview | ScienceDirect Topics
网页Thymine dimers occur when DNA is exposed to UV radiation. The most common form, cis-syn cyclobutane pyrimidine dimer (CPD), is a strong block to replicative DNA polymerases.
Pyrimidine Dimer - an overview | ScienceDirect Topics
网页A pyrimidine dimer is an intrastrand DNA cross-link caused by exposure to ultraviolet light, which can block DNA replication and transcription. Various DNA repair mechanisms exist to remove pyrimidine dimers, as defects in their removal can lead to diseases and cancer in humans.
9.3: DNA Repair - Biology LibreTexts
网页Pyrimidine Dimerization UV light exposure of DNA can cause adjacent pyrimidines (commonly thymines; less often, cytosines) on a DNA strand to dimerize. Pyrimidine dimers form at a rate of a bit less than 100 per cell per day!
DNA Repair - The Cell - NCBI Bookshelf
网页As might be expected from the fact that solar UV irradiation is a major source of DNA damage for diverse cell types, the repair of pyrimidine dimers by photoreactivation is common to a variety of prokaryotic and eukaryotic cells, including E. coli, yeasts, and some species of plants and animals.
Mechanisms of UV-induced mutations and skin cancer
网页2020年3月19日 · The dimerization involves the formation of cis-syn cyclobutane pyrimidine dimers (CPDs) as the most prominent lesion in double-stranded DNA, or of pyrimidine (6–4) pyrimidone photoproducts [(6–4) photoproducts; (6–4)PPs] as the second most frequent DNA lesion in the UVB range (Pfeifer 1997).
Pyrimidine dimers - Vocab, Definition, and Must Know Facts
网页Pyrimidine dimers are a type of DNA damage that occurs when two adjacent pyrimidine bases, usually thymine, bond together due to ultraviolet (UV) radiation.
7.3: Ionizing Radiation - Biology LibreTexts
网页2023年6月20日 · Ultraviolet radiation with a wavelength of 260 nm will form pyrimidine dimers between adjacent pyrimidines in the DNA. The dimers can be one of two types (Figure 7.11). The major product is a cytobutane-containing thymine dimer (between C5 and C6 of adjacent T's).
Pyrimidine Dimer - an overview | ScienceDirect Topics
网页Pyrimidine dimers are structures that form between two of four nucleotide bases that make up DNA: the nucleotides cytosine and thymine, which are members of the chemical family called pyrimidines. From: Animal Biotechnology, 2014
All You Need Is Light. Photorepair of UV-Induced Pyrimidine Dimers
网页2020年11月4日 · Cyclobutane pyrimidine dimers (CPDs), 7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) and single strand breaks (SSBs) are formed upon UV-A, UV-B and UV-C radiation. CPDs can undergo photoreversion to undamaged bases upon UV-C radiation (a).
- 某些结果已被删除