Acetyllysine - Wikipedia
网页Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine: this article is about N-ε-acetyl-L-lysine; the other form is N-α-acetyl-L-lysine. In proteins, the acetylation of lysine residues is …
Lysine acetylation regulates the interaction between proteins …
网页2021年11月9日 · Here, the authors map lysine acetylation predominantly in membrane-interaction regions in peripheral membrane proteins and show with three candidate proteins how lysine acetylation is a...
Acetylated-Lysine Antibody | Cell Signaling Technology
网页The antibody recognizes acetylated lysine in a wide range of sequence contexts. It has been demonstrated to recognize acetylated histones, p53, CBP, PCAF and chemically …
The growing landscape of lysine acetylation links metabolism and …
网页2014年7月23日 · Acetylation-mediated cellular signalling involves three classes of proteins: 'writers' or lysine acetyltransferases (KATs), which add acetyl groups to proteins; 'erasers' or lysine deacetylases...
Protein acylation: mechanisms, biological functions and …
网页2022年12月29日 · P38 mitogen-activated protein kinase (MAPK) was reported to be reversibly acetylated by p300/CREB binding protein-associated factor (PCAF)/p300 and histone deacetylases 3 (HDAC3) at K53, a...
Lysine Acetylation Goes Global: From Epigenetics to Metabolism …
网页Lysine acetylation describes the transfer of an acetyl group from acetyl-coenzyme A (acetyl-CoA) to the primary amine in the ε-position of the lysine side chain within a protein, a process that leads to neutralization of the position’s positive electrostatic charge.
Lysine acetylation regulates the interaction between proteins and ...
网页Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates the function of membrane proteins. Here, the authors map lysine acetylation predominantly in membrane-interaction regions in peripheral membrane proteins and show with three candidate proteins how lysine ...
Lysine Acetylation Is a Highly Abundant and Evolutionarily …
网页Acetylated lysine containing peptides identified with a MASCOT score of 25 were manually verified by the method described previously . Western Blotting Analysis— E. coli …
Lysine Acetylation Targets Protein Complexes and Co-Regulates ... - Science
网页2009年7月16日 · Lysine acetylation is a reversible posttranslational modification of proteins and plays a key role in regulating gene expression. Technological limitations have so far prevented a global analysis of lysine acetylation’s cellular roles.
Lysine Acetylation of Proteins and Its Characterization in Human ...
网页More recently, high-quality antibodies that recognize acetylated lysine residues present in acetylated proteins and improved proteomic methodologies have facilitated the discovery that acetylation occurs on numerous cellular proteins and allowed characterization of the dynamics and functional effects of many acetylation events.