Acetylation - Wikipedia
网页In chemistry, acetylation is an organic esterification reaction with acetic acid. It introduces an acetyl group into a chemical compound. Such compounds are termed acetate esters or simply acetates. Deacetylation is the opposite reaction, the removal of an acetyl group from a chemical compound.
Acetylation - Explain Acetylation, Reaction of acetylation with ...
网页Acetylation is a chemical reaction in which a hydrogen atom is substituted for an acetyl group (CH 3 C=O group) in a compound. The products formed in acetylation reactions typically have an acetoxy functional group.
Protein acylation: mechanisms, biological functions and …
网页2022年12月29日 — In this review, we provide an overview of the expanding landscape of nonhistone protein acylation, mainly including acetylation, succinylaton, malonylation, crotonylation, β-hydroxybutyrylation...
Protein acylation: mechanisms, biological functions and …
网页Protein kinases bind ATP and use it to phosphorylate other proteins. Acetylation is known to regulate kinase activity through impairing or enhancing ATP binding. Generally, there is a conserved lysine residue in the ATP-binding pocket of protein kinases, which could be acetylated to affect kinase catalytic activity.
What is Acetylation? - News-Medical.net
网页2023年2月23日 — Acetylation is a chemical reaction that is called ethanoylation in the IUPAC nomenclature. It describes a reaction that introduces an acetyl functional group into a chemical compound.
Acetylation - an overview | ScienceDirect Topics
网页Acetylation is a reversible PTM of lysine residues of proteins occurring in eukaryotic organisms. Acetylation occurs via action of histone acetyltransferases (HATs), while reversal is carried out by histone deacetylases (HDACs); note that lysine deacetylation (KDAC) and HDAC are frequently used interchangeably in the literature.
The world of protein acetylation - PubMed
网页Acetylation is one of the major post-translational protein modifications in the cell, with manifold effects on the protein level as well as on the metabolome level. The acetyl group, donated by the metabolite acetyl-coenzyme A, can be co- or post-translationally attached to either the α-amino group ….
Acetylation - an overview | ScienceDirect Topics
网页Acetylation refers to a reversible modification on proteins, particularly lysine residues in histone proteins, that can influence chromatin structure and gene expression levels. This process is extensively studied in molecular and cell biology, although the functional consequences of acetylation on other proteins are not well understood.
Special issue on protein acetylation: from molecular modification …
网页2018年7月27日 — Protein acetylation is one of the major post-translational modifications (PTMs) that regulates various biological processes in eukaryotic cells. By transferring the acetyl functional...
Mechanisms, Detection, and Relevance of Protein Acetylation in ...
网页2019年4月9日 — To study acetylation in an organism, it is important to generate sensitive and appropriate analytical methods and protocols to detect and quantify lysine acetylation. A simple and effective method is to perform an antiacetyllysine (K ac) Western blot analysis of proteins harvested from the organism of interest using commercially available anti ...