Anandamide - Wikipedia
Anandamide (ANA), also referred to as N-arachidonoylethanolamine (AEA) is a fatty acid neurotransmitter belonging to the fatty acid derivative group known as N-acylethanolamine (NAE). Anandamide takes its name from the Sanskrit word ananda, …
花生四烯乙醇胺 - 维基百科，自由的百科全书
花生四烯乙醇胺，又名 N-花生四烯乙醇胺 或 AEA，是一種內源性的 大麻醇類 神經傳導物質。 命名取自 梵文 （和 印度半島 宗教用語）中的「阿難陀 （ananda）」，意为“喜悅、極樂、欣喜”，以及 醯胺 [3][4]。 它是由N-花生四烯酰磷脂酰乙醇胺透過多種途徑合成 [5]。 花生四烯乙醇胺，主要是由脂肪酸醯胺水解酶 (FAAH)將其 降解 成 乙醇胺 和 花生四烯酸。 如此，脂肪酸醯胺水解酶 (FAAH)的抑制物導致花生四烯乙醇胺層級的提升，並被用于治療 [6][7]。 花生四烯乙醇胺的結 …
Brain activity of anandamide: a rewarding bliss? - PMC
Anandamide is a lipid mediator that acts as an endogenous ligand of CB1 receptors. These receptors are also the primary molecular target responsible for the pharmacological effects of Δ9-tetrahydrocannabinol, the psychoactive ingredient in Cannabis ...
Anandamide - an overview | ScienceDirect Topics
Anandamide was the first endogenous ligand of cannabinoid receptors to be discovered in 1992. Yet, this compound also efficiently activates receptors specific for capsaicin, known as vanilloid type 1 receptors (VR1). Whether anandamide is a physiological VR1 ligand is controversial.
Anandamide | C22H37NO2 | CID 5281969 - PubChem
Anandamide is an N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine. It has a role as a neurotransmitter, a vasodilator agent and a human blood serum metabolite.
The endocannabinoid system, anandamide and the regulation of …
2003年8月22日 · Anandamide (N -arachidonoylethanolamine; AEA) and 2-arachidonoylglycerol (2-AG) are the main endogenous agonists of cannabinoid receptors able to mimic several pharmacological effects of...
Anandamide - an overview | ScienceDirect Topics
Anandamide is a CB1 agonist that interacts with vanilloid receptors to transduce and regulate nociceptive signals (including pain and itch) to the peripheral nervous system. From: A Comprehensive Guide to Hidradenitis Suppurativa, 2022
The rise and fall of anandamide: processes that control ... - PubMed
Anandamide is an endocannabinoid derived from arachidonic acid-containing membrane lipids and has numerous biological functions. Its effects are primarily mediated by the cannabinoid receptors CB1 and CB2, and the vanilloid TRPV1 receptor. Anandamide is known to be involved in sleeping and eating pa …
Anandamide: an update - PubMed
The prime endogenous cannabinoids are arachidonoylethanolamide also called anandamide and 2-arachidonoylglycerol. Recent pharmacological advances point out that this system of molecules are in initial stages and by updating our current knowledge, we could innovatively design molecules for suitable interventions that could be potentially ...
The rise and fall of anandamide: processes that control synthesis ...
2021年3月13日 · Anandamide is known to be involved in sleeping and eating patterns as well as pleasure enhancement and pain relief. This manuscript provides a review of anandamide synthesis, degradation, and storage and hence the homeostasis of …