Chemokine - Wikipedia
Chemokines (from Ancient Greek χῠμείᾱ (khumeíā) 'alchemy' and κῑ́νησῐς (kī́nēsis) 'movement'), or chemotactic cytokines, are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. [ 1 ][ 2 ] In addition to playin...
A guide to chemokines and their receptors - PMC - National …
2018年4月24日 · The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are best known for their ability to stimulate the migration of cells, most notably white blood cells (leukocytes).
Chemokines - Definition, Function and Quiz - Biology Dictionary
2017年7月4日 · Chemokines are signaling proteins secreted by cells of the immune system that stimulate the movement of other cells. Their name is reminiscent of their function since it is derived from chemotaxis, or movement in response to a chemical stimulus, and cytokines, which are small proteins implicated in cell signaling.
Chemokine | Immune Response, Inflammation & Cytokines
Chemokine, any of a group of small hormonelike molecules that are secreted by cells and that stimulate the movement of cells of the immune system toward specific sites in the body. Chemokines are a type of cytokine (a short-lived secreted protein that regulates the function of nearby cells) and may.
Chemokines: the past, the present and the future
2018年3月26日 · The first biologically active chemokines were discovered in the late 1980s and early 1990s, based on the presence of leukocyte chemoattractant activity present in the culture supernatants of human...
A guide to chemokines and their receptors - PubMed
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G protein-coupled heptahelical chemokine receptors. They are best known for their ability to stimulate the migration of cells, …
Chemokines: Introduction | British Society for Immunology
Chemokines are a family of chemoattractant cytokines (small proteins secreted by cells that influence the immune system) which play a vital role in cell migration through venules from blood into tissue and vice versa, and in the induction of cell movement in response to a chemical (chemokine) gradient by a process known as chemotaxis (Figure 1).
Chemokine - an overview | ScienceDirect Topics
Chemokines are inflammatory mediators that have a chemotactic function in attracting leukocytes to tissues. They are produced by a number of cells, including endothelial cells, fibroblasts, and lymphocytes, and are secreted and bound to receptors on target cells (eg, monocytes and lymphocytes).
The chemokines CXCL8 and CXCL12: molecular and functional
2023年2月1日 · Chemokines are an indispensable component of our immune system through the regulation of directional migration and activation of leukocytes. CXCL8 is the most potent human neutrophil-attracting...
Chemokines in homeostasis and diseases | Cellular & Molecular …
2018年1月29日 · This review introduces the functional array and signals of multiple chemokine GPCRs in guiding leukocyte trafficking as well as their roles in homeostasis, inflammation, immune responses and...