Mammalian Germ Cell Development: From Mechanism to In …
In this article, Saitou provides a brief overview of key investigations, including those exploring the mechanism of mammalian germ cell specification and epigenetic reprogramming, that have …
Genetics of germ cell development | Nature Reviews Genetics
Oct 9, 2012 · Germ cells are specialized cells that are responsible for transmitting the genome of an individual organism to its offspring. The defining characteristic of the germ cells is their...
Dispatch Germ cell development: Anchoring and pulling forces …
Dec 16, 2024 · In germ cell development, embryonic primordial germ cells migrate to the developing gonads, where they give rise to differentiating oocytes and spermatocytes. The …
Phase Separation in Germ Cells and Development - Cell Press
How germ cells develop, function, and eventually give rise to entirely new organisms is an important question in biology. A growing body of evidence suggests that phase separation …
Mammalian Germ Cell Development: From Mechanism to In …
Apr 13, 2021 · The germ cell lineage gives rise to totipotency and perpetuates and diversifies genetic as well as epigenetic information. Specifically, germ cells undergo epigenetic …
Human Germline Cell Development: from the Perspective of Single-Cell ...
Oct 17, 2019 · In this review, we discuss progress in analyzing the development of human germline cells, including preimplantation and implantation embryos, fetal germ cells (FGCs), …
Models of germ cell development and their application for …
Indeed, these models allow (1) examination of stages of germ cell development that are not easily accessible in mammals (specifically early development of the female germline), (2) the …
Phase Separation in Germ Cells and Development - ScienceDirect
Oct 2, 2020 · How germ cells develop, function, and eventually give rise to entirely new organisms is an important question in biology. A growing body of evidence suggests that phase …
Germ cell determination and the developmental origin of germ cell ...
Apr 16, 2021 · We compare germline development across diverse species to consider when and how determined (committed) germ cells are first distinguished from their germline precursors. …
Germline development - Wikipedia
The germ plasm effectively turns off gene expression to render the genome of the cell inert. Cells expressing germ plasm become primordial germ cells (PGCs) which will then give rise to the …