preparation of amines - chemguide
网页This page looks at the preparation of amines from halogenoalkanes (also known as haloalkanes or alkyl halides) and from nitriles. It only deals with amines where the functional group is not attached directly to a benzene ring.
Preparation of Amines1 - Chemistry LibreTexts
网页2023年1月23日 · Making amines from halogenoalkanes. The halogenoalkane is heated with a concentrated solution of ammonia in ethanol. The reaction is carried out in a sealed tube. You couldn't heat this mixture under reflux, because the ammonia would simply escape up the condenser as a gas.
multiple nucleophilic substitution - halogenoalkanes and ammonia
网页This page looks at further substitution in the nucleophilic substitution reaction between halogenoalkanes and ammonia following the formation of the primary amine. You could also think of this as a description of how primary, secondary and tertiary amines act as nucleophiles in a sequence of reactions with a halogenoalkane.
21.5: Synthesis of Amines by Alkylation - Chemistry LibreTexts
网页This page summarises the reactions of amines as nucleophiles. This includes their reactions with halogenoalkanes (haloalkanes or alkyl halides), with acyl chlorides (acid chlorides) and with acid anhydrides.
Nucleophilic Substitution | AQA A Level Chemistry Revision Notes …
网页Revision notes on 3.7.3 Nucleophilic Substitution for the AQA A Level Chemistry syllabus, written by the Chemistry experts at Save My Exams.
23.2: Preparation of Amines - Chemistry LibreTexts
网页Primary amines can be synthesized by alkylation of ammonia. A large excess of ammonia is used if the primary amine is the desired product. Haloalkanes react with amines to give a corresponding alkyl-substituted amine, with the release of a halogen acid.
Nucleophilic Substitution of Halogenoalkanes with Ammonia ... - YouTube
网页Outlining the nucleophilic substitution of halogenoalkanes with ammonia, NH3, to form primary amines, including further substitution reactions to form secondary and tertiary amines as well as...
网页This chapter describes nucleophilic substitution reactions of haloalkanes, alcohols, amines, and compounds related to them. These are ionic reactions in which one group on the molecule (a leaving group) is replaced by another group (a nucleophile).
nucleophilic substitution - halogenoalkanes and ammonia
网页This page gives you the facts and simple, uncluttered mechanisms for the nucleophilic substitution reactions between halogenoalkanes and ammonia to produce primary amines. If you want the mechanisms explained to you in detail, there is a link at the bottom of the page.
23.2. Preparation of Amines | Organic Chemistry II - Lumen …
网页Haloalkanes react with amines to give a corresponding alkyl-substituted amine, with the release of a halogen acid. Such reactions, which are most useful for alkyl iodides and bromides, are rarely employed because the degree of alkylation is difficult to control.