Potassium leak channels and the KCNK family of two-p-domain ... - Nature
2001年3月1日 · KCNK channels are easy to identify because of their unique structure — they possess two pore-forming domains in each subunit. The new channels function in a most remarkable fashion: they are...
KCNK2 - Wikipedia
Potassium channel subfamily K member 2, also known as TREK-1, is a protein that in humans is encoded by the KCNK2 gene. [5][6][7] This gene encodes K 2P 2.1, a lipid-gated ion channel belonging to the two-pore-domain background potassium channel protein family.
Potassium leak channels and the KCNK family of two-P-domain …
KCNK channels are easy to identify because of their unique structure--they possess two preforming domains in each subunit. The new channels function in a most remarkable fashion: they are highly regulated, potassium-selective leak channels.
KCNK1 Gene - GeneCards | KCNK1 Protein | KCNK1 Antibody
2024年12月9日 · KCNK1 (Potassium Two Pore Domain Channel Subfamily K Member 1) is a Protein Coding gene. Diseases associated with KCNK1 include Hypokalemia and Adrenal Cortical Adenocarcinoma. Among its related pathways are Sweet Taste Signaling and Cardiac conduction.
KCNK2 Gene - GeneCards | KCNK2 Protein | KCNK2 Antibody
2024年12月9日 · KCNK2 (Potassium Two Pore Domain Channel Subfamily K Member 2) is a Protein Coding gene. Diseases associated with KCNK2 include Bladder Neck Obstruction and Dentin Sensitivity. Among its related pathways are Sweet Taste Signaling and …
KCNK channels are easy to identify because of their unique structure — they possess two poreforming domains in each subunit. The new channels function in a most remarkable fashion: they are highly regulated, potassium-selective leak channels.
KCNK1 - Wikipedia
Potassium channel subfamily K member 1 is a protein that in humans is encoded by the KCNK1 gene. [5][6][7] This gene encodes K 2P 1.1, a member of the superfamily of potassium channel proteins containing two pore-forming P domains.
Integrative Analysis of KCNK Genes and Establishment of a …
2022年5月17日 · Two-pore domains potassium channel subunits, encoded by KCNK genes, play vital roles in breast cancer progression. However, the characteristics of most KCNK genes in breast cancer has yet to be clarified. In this study, we comprehensively analyzed the expression, alteration, prognosis, and biological functions of various KCNKs in breast cancer.
TASK4 (KCNK17)通道是一个开路整流器,主要在生理K+ 浓度下向外传递电流,在碱性pH下被激活,在肺、胃、胎盘、胆囊、心脏等多种组织中广泛表达。
K2P钾通道机制和药理学的结构见解,Journal of Molecular Biology
K 2P ( KCNK ) 钾通道类别包括一个离子通道家族，该家族产生钾泄漏电流，可对抗兴奋并稳定大脑、心血管系统、免疫系统和感觉器官细胞中的静息膜电位。 由于其广泛的组织分布，K 2P s 有助于许多生理和病理生理过程，包括麻醉、疼痛、心律失常、缺血、高血压、偏头痛、眼内压调节和肺损伤反应。 六同聚体 K 2P的结构研究 s 建立了该通道系列的基本架构，揭示了 K 2P函数中涉及的关键运动部件，揭示了 K 2P 选择性滤波器 (SF) C 型门中不对称收缩和膨胀运动的重要 …