Toll-like receptor 9 - Wikipedia
网页Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. [5] TLR9 has also been designated as CD289 (cluster of differentiation 289). It is a member of the toll-like receptor (TLR) family.
Surface toll-like receptor 9 on immune cells and its …
网页2023年9月1日 · Toll like receptor 9 (TLR9) has been considered as a crucial intracellular pattern recognition receptor in the immune system, which can directly or indirectly mediate innate and adaptive immune responses by recognizing CpG DNA in endosomes to initiate its downstream signaling.
Toll-Like Receptors (TLRs): Structure, Functions, Signaling, and …
网页2021年9月12日 · Toll-like receptors (TLRs) are the important mediators of inflammatory pathways in the gut which play a major role in mediating the immune responses towards a wide variety of pathogen-derived ligands and link …
TLR9 toll like receptor 9 [ (human)] - National Center for ...
网页2024年8月22日 · The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.
Toll-like receptor 9 agonists and combination therapies ... - Nature
网页2022年7月28日 · Toll-like receptor 9 (TLR9) agonists have been extensively investigated as therapeutics in monotherapy or combination therapies for the treatment of cancer, infectious diseases and...
TLR9 Gene - GeneCards | TLR9 Protein | TLR9 Antibody
网页2024年8月6日 · Complete information for TLR9 gene (Protein Coding), Toll Like Receptor 9, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium.
Cyclical palmitoylation regulates TLR9 signalling and systemic ...
网页2024年1月2日 · Toll-like receptor 9 (TLR9) recognizes self-DNA and plays intricate roles in systemic lupus erythematosus (SLE). However, the molecular mechanism regulating the endosomal TLR9 response is...
The Biology of Toll-Like Receptor 9 and Its Role in Cancer
网页Toll-like receptor 9 (TLR9) plays a fundamental role in innate immune responses through pathogen-associated and danger-associated molecular pattern recognition.
TLR9 - an overview | ScienceDirect Topics
网页TLR9 is a receptor that recognizes specific DNA motifs found in both bacterial and viral DNA, and has the potential to be targeted for adjuvants. Recent studies suggest that TLR9 may play a role in the production of autoantibodies, which …
Toll-Like Receptor 9 Agonists in Cancer - PubMed
网页2020年10月9日 · In this review article, we describe the distribution, structure and signaling of TLR9; discuss the results of preclinical studies of TLR9 agonists; and review ongoing clinical trials of TLR9 agonists singly and in combination …