Thalassemia - Wikipedia
Thalassemias are inherited blood disorders that result in abnormal hemoglobin. [7] . Symptoms depend on the type of thalassemia and can vary from none to severe. [1] .
地中海贫血症 - 百度百科
地中海贫血（thalassemia，简称地贫）又称海洋性贫血，是临床上常见的遗传性溶血性贫血。 多见于东南亚、 地中海 等地区 [1]，最早在地中海沿岸的意大利、希腊、马耳他等地区发现，故称地中海贫血。 地中海贫血是一种 血红蛋白 异常的疾病，由于 常染色体 基因缺陷而导致的一种遗传性疾病。 由于调控珠蛋白合成的基因缺失或突变，导致构成血红蛋白的α链和β链珠蛋白的合成比例失衡，红细胞寿命缩短的一种 溶血性贫血 [2]。 地中海贫血和普通贫血发病机制不同，普通贫血 …
Thalassemia: Types, Traits, Symptoms & Treatment - Cleveland Clinic
2022年6月3日 · Thalassemia is an inherited blood disorder that affects your body’s ability to produce hemoglobin and healthy red blood cells. Types include alpha and beta thalassemia. Thalassemia may cause you to experience anemia-like symptoms that range from mild to severe. Treatment can consist of blood transfusions and iron chelation therapy.
Thalassaemia - NHS
Thalassaemia is the name for a group of inherited conditions that affect a substance in the blood called haemoglobin. People with thalassaemia produce either no or too little haemoglobin, which is used by red blood cells to carry oxygen around the body. This can make them very anaemic (tired, short of breath and pale).
Thalassemia: Causes, Symptoms, Diagnosis, and Treatment - Healthline
2019年11月14日 · Thalassemia is an inherited blood disorder in which the body makes an abnormal form of hemoglobin. Hemoglobin is the protein molecule in red blood cells that carries oxygen. The disorder...
Thalassemia - StatPearls - NCBI Bookshelf
2023年8月8日 · Thalassemia is a heterogeneous group of blood disorders affecting the hemoglobin genes and resulting in ineffective erythropoiesis. The decreased production of hemoglobin results in anemia in early age and frequent blood transfusions are required to keep up the hemoglobin levels.
Thalassaemia | Alpha & Beta - Geeky Medics
2022年12月11日 · Thalassaemia is a group of genetic disorders that lead to reduced haemoglobin in red blood cells. They are classified according to the globin chain which is affected and the severity of the resulting clinical picture, which ranges from asymptomatic to fatal.
Thalassaemia - The Lancet
2022年6月9日 · Thalassaemia is a diverse group of genetic disorders with a worldwide distribution affecting globin chain synthesis. The pathogenesis of thalassaemia lies in the unbalanced globin chain production, leading to ineffective erythropoiesis, increased haemolysis, and deranged iron homoeostasis.
Thalassaemia - PubMed
2018年1月13日 · Inherited haemoglobin disorders, including thalassaemia and sickle-cell disease, are the most common monogenic diseases worldwide. Several clinical forms of α-thalassaemia and β-thalassaemia, including the co-inheritance of β-thalassaemia with haemoglobin E resulting in haemoglobin E/β-thalassaemia, …
Thalassaemia - PubMed
2022年6月18日 · Thalassaemia is a diverse group of genetic disorders with a worldwide distribution affecting globin chain synthesis. The pathogenesis of thalassaemia lies in the unbalanced globin chain production, leading to ineffective erythropoiesis, increased haemolysis, and deranged iron homoeostasis.