Cardiotoxicity - Wikipedia
Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity. [1] . This can cause heart failure, arrhythmia, myocarditis, and cardiomyopathy in patients. [2] . Some effects are reversible, while in others, permanent damage requiring further treatment may arise.
Cardiotoxicity: Heart Damage from Cancer Treatment - Cleveland Clinic
Cardiotoxicity refers to any heart damage arising from cancer treatment. It isn’t common overall but may be common in people who take certain chemotherapy or targeted therapy drugs. You may also develop heart problems after having radiation therapy to the chest. Cardiotoxicity sometimes develops years after cancer treatment. What is cardiotoxicity?
Cardiotoxicity: Causes and Symptoms - Medicover Hospitals
Cardiotoxicity is a condition resulting from the detrimental impact of certain substances or medications on the heart muscle. It manifests as a range of cardiovascular dysfunctions, from mild heart muscle impairment to severe heart failure.
Cardiotoxicity - an overview | ScienceDirect Topics
Cardiotoxicity is a broad term that encompasses asymptomatic detectable structural changes on the heart, which can manifest by the onset of arrhythmias, elevation in cardiac biomarkers related to stress and myocardial injury, and LV dysfunction (systolic and diastolic) without symptoms of …
Comprehensive review of cardiovascular toxicity of drugs and …
Cardiovascular diseases are a leading cause of morbidity and mortality in most developed countries of the world. Pharmaceuticals, illicit drugs, and toxins can significantly contribute to the overall cardiovascular burden and thus deserve attention.
Cardiotoxicity | Division of Cancer Prevention
2022年12月14日 · Chemotherapy and radiation therapy, as well as newer forms of cancer treatment like immune system therapies, can cause or worsen cardiovascular side effects, including high blood pressure, abnormal heart rhythms, and heart failure.
What is cardiotoxicity? | Baker Institute
Cardiotoxicity occurs when something interferes with the heart’s ability to do its job. This can lead to conditions like heart failure, where the heart doesn’t pump blood as efficiently as it should, or arrhythmias, which are irregular heartbeats. It can also affect blood vessels, causing atherosclerosis and coronary artery disease.
Drugs That May Cause or Exacerbate Heart Failure:
2016年7月11日 · Drugs may cause or exacerbate HF by causing direct myocardial toxicity; by negative inotropic, lusitropic, or chronotropic effects; by exacerbating hypertension; by delivering a high sodium load; or by drug-drug interactions that limit the beneficial effects of HF medications.
Cardiac Toxicity - OncoLink
Cardiac (heart) toxicity is a side effect of cancer treatment that causes damage to the heart muscle or valves. Both chemotherapy and radiation can lead to cardiac toxicity, based on the type of medication (s) you had and where radiation treatment was given.
Cardiotoxicity of Anticancer Drugs: Molecular Mechanisms and …
In this review, we summarize the knowledge regarding the cellular and molecular mechanisms contributing to the onset of cardiotoxicity associated with common classes of chemotherapy and targeted therapy drugs.