Fucose - Wikipedia
Fucose is a hexose deoxy sugar with the chemical formula C 6 H 12 O 5. It is found on N-linked glycans on the mammalian, insect and plant cell surface. Fucose is the fundamental sub-unit of the seaweed polysaccharide fucoidan. [1] The α(1→3) linked core of fucoidan is a suspected carbohydrate antigen for IgE-mediated allergy. [2]
Biological functions of fucose in mammals - PMC
In this review, we summarize the known roles of fucose in mammalian physiology and pathophysiology. Additionally, we discuss recent therapeutic advances for cancer and other diseases that are a direct result of our improved understanding of the role that fucose plays in …
Fucose - an overview | ScienceDirect Topics
Fucose (Fuc), a monosaccharide present at the core or the termini of glycans, critically regulates various biological phenomena and is associated with various diseases. Specifically detecting Fuc residues or inhibiting the fucosylation pathway is pivotal in understanding the mechanisms of how fucosylated glycans are related to biological ...
Fucose: biosynthesis and biological function in mammals
2003年7月1日 · Fucose is a deoxyhexose that is present in a wide variety of organisms. In mammals, fucose-containing glycans have important roles in blood transfusion reactions, selectin-mediated leukocyte-endothelial adhesion, host–microbe interactions, and numerous ontogenic events, including signaling events by the Notch receptor family.
What is Fucose? - Spiegato
Fucose is an essential hexose deoxy sugar the human body needs to optimally communicate from cell to cell. Simply put, it plays an important role in transmitting information in the brain. Research studies show that this sugar stimulates brain development and can also influence the brain to be able to create long-term memories.
Fucose - an overview | ScienceDirect Topics
Fucose is a hexose deoxy sugar with the chemical formula C6H12O5 and is the fundamental sub unit of the fucoidan polysaccharide. From: Carbohydrate Polymers, 2012
Fucose - an overview | ScienceDirect Topics
Fucose is a rare monosaccharide that has antitumor, intestinal disease-relieving, and microbial virulence-regulating properties. It is used in functional foods, skincare products, and as an emulsifier in the food industry. Additionally, it can serve as a diagnostic marker for tumors and immune-related diseases.
Unmasking Fucosylation: from Cell Adhesion to Immune
2018年5月17日 · Fucose is necessary for many critical cell adhesion and signaling events. Genetic modulation or modulation by fucose-specific reagents has revealed exciting new biology and opened new opportunities for the treatment of human diseases.
Biological functions of fucose in mammals - PubMed
2017年7月1日 · Fucose is a 6-deoxy hexose in the l-configuration found in a large variety of different organisms. In mammals, fucose is incorporated into N-glycans, O-glycans and glycolipids by 13 fucosyltransferases, all of which utilize the nucleotide-charged form, GDP …
Significance of fucose in intestinal health and disease
The deoxyhexose sugar L-fucose is important for many biological processes within the human body and the associated microbiota. This carbohydrate is abundant in host gut mucosal surfaces, numerous microbial cell surface structures, and some dietary carbohydrates.