Glucanase - Wikipedia
Glucanases are enzymes that break down large polysaccharides via hydrolysis. The product of the hydrolysis reaction is called a glucan, a linear polysaccharide made of up to 1200 glucose monomers, held together with glycosidic bonds. [1] .
NGLY1 - Wikipedia
PNGase also known as N-glycanase 1 (EC 3.5.1.52) or peptide-N (4)- (N-acetyl-beta-glucosaminyl)asparagine amidase is an enzyme that in humans is encoded by the NGLY1 gene.
N-聚糖酶 - 百度百科
N-glycanase 定 义 细胞质基质中负责切除错误折叠糖蛋白中天冬酰胺连接的寡糖链的酶。酶的作用有助于后续的蛋白质降解。 应用学科 细胞生物学（一级学科），细胞化学（二级学科）
The cytoplasmic peptide:N-glycanase (NGLY1) - ScienceDirect
Feb 10, 2016 · The cytosolic PNGase (peptide:N-glycanase; NGLY1/Ngly1 in human/mice) is a well-conserved deglycosylating enzyme that is involved in the non-lysosomal degradation of N-glycoproteins. PNGase releases intact N- glycans from glycoproteins and is involved in the clearance of misfolded glycoproteins from the cytosol.
Glucanase - an overview | ScienceDirect Topics
Glucanases are enzymes that break down glucan, a polysaccharide made of several glucose subunits. You might find these chapters and articles relevant to this topic. Arvind Kumar, Ram Naraian, in New and Future Developments in Microbial Biotechnology and Bioengineering, 2019.
The cytoplasmic peptide:N-glycanase (NGLY1) - Structure
Feb 10, 2016 · NGLY1/Ngly1 is a cytosolic peptide:N-glycanase, i.e. de-N-glycosylating enzyme acting on N-glycoproteins in mammals, generating free, unconjugated N-glycans and deglycosylated peptides in which the N-glycosylated asparagine residues are converted to aspartates. This enzyme is known to be involved in …
Physiological and molecular functions of the cytosolic peptide:N-glycanase
May 1, 2015 · The cytosolic peptide:N-glycanase (PNGase) (peptide-N 4-(N-acetyl-β-glucosaminyl) asparagine amidase; also known as N-glycanase or glycoamidase, E.C. 3.5.1.52) has been shown to be involved in the degradation of misfolded glycoproteins by the process called endoplasmic reticulum-associated degradation (ERAD).
NGLY1 gene - MedlinePlus
The NGLY1 gene provides instructions for making an enzyme called N -glycanase 1. This enzyme is involved in a process called deglycosylation, by which chains of sugar molecules (glycans) are removed from proteins. Specifically, N -glycanase 1 removes glycans from misfolded proteins.
Enzyme assay of endogenous activity of peptide-N-glycanase …
Sep 15, 2021 · The cytosolic peptide: N -glycanase (PNGase; NGLY1 in mammal) is an enzyme that catalyzes the hydrolysis of an amide bond between glycosylated asparagine residues on proteins and proximal GlcNAc residues of N -glycans (1).
N-glycanase NGLY1 regulates mitochondrial homeostasis and …
Oct 18, 2024 · The N-glycanase 1 (NGLY1), also known as peptide:N-glycanase (PNGase), is an evolutionarily conserved enzyme that removes N-glycans from glycosylated proteins in the cytosol (Suzuki et al., 2016). NGLY1 plays a crucial role in quality …