BioLuminate | Schrödinger Biologics
Model antibody structures using a fully guided, specialized workflow incorporating de novo CDR loop sampling; Leverage advanced protein sequence analysis tools, including annotation capabilities
Introduction to computational antibody engineering
Structure-based workflows for assessing and improving stability, affinity, and ‘humanness’ of antibody therapeutics with BioLuminate. 5 weeks / ~20 hours to complete. Introductory. $575 for non-student users. $150 for student / post-doc. When registering for the course, you will be able to choose your preferred start and end date.
Life Science Online Certification Courses - Schrödinger
Structure-based workflows for assessing and improving the developability, stability, affinity, and ‘humanness’ of antibody therapeutics with BioLuminate. Molecular and periodic quantum mechanics, all atom molecular dynamics, and coarse-grained approaches for studying active pharmaceutical ingredients and their formulations.
计算机辅助药物设计WORKSHOP (第二期)-清华大学药学院
Watermap绘制了蛋白质结合位点中水分子的位置和热力学性质，并以图形方式显示计算结果，便于水合位点的可视化，使SAR的解释更直观，提供了可能提高先导化合物活性和选择性的优化设计路线。 本教程将演示如何设置watermap计算，分析计算结果，以及根据计算结果来指导化合物的设计。 Antibody Modeling.
薛定谔BioLuminate使用教程 - 哔哩哔哩
薛定谔BioLuminate使用教程共计11条视频，包括：BioLuminate - Antibody Modeling Part 1 of 2-L_y6kNdSDfU、BioLuminate - Antibody Modeling Part 2 of 2-aO6-C2tOt0s、BioLuminate - Examining Sequences-sBKbsA5jo-U等，UP主更多精彩视频，请关注UP账号。
Biologics Suite (BioLuminate) Training Videos - 哔哩哔哩
Biologics Suite (BioLuminate) Training Videos共计12条视频，包括：BioLuminate - Main Window、BioLuminate - Toggle Table、BioLuminate - Examining Sequences等，UP主更多精彩视频，请关注UP账号。
Antibody structure determination using a combination of …
We present the blinded prediction results in the Second Antibody Modeling Assessment (AMA-II) using a fully automatic antibody structure prediction method implemented in the programs BioLuminate and Prime. We have developed a novel knowledge based approach to model the CDR loops, using a combination …
I want to calculate the interaction energy between a residue and ...
If you want to determine the effect of mutating a residue on the binding free energy of two proteins (an antibody and an antigen, for example), you can use the BioLuminate Residue Scanning tool (Tasks → Residue Scanning in the BioLuminate interface).
Bioluminate 1-4 - NodePit
[Requires: Bioluminate] The antibody structure can be split into Fc, Fab and Fv domains. The node scans proteins for residues that are candidates for mutation and evaluate the stability and affinity of the mutated structures.
How to import an antibody database file and make it active
Launch the Antibody Structure Prediction panel in BioLuminate; In the Framework section, click on the "Choose Database" option in the top right of the panel; In the dialog box, click on "Add Database..." and browse the file system for the downloaded file (the default file name is "antibody_full.db"). The database is added to the list of ...