Chitosan Nanolayered Cisplatin-Loaded Lipid Nanoparticles
2016年11月25日 · In this study, cisplatin (CDDP)-loaded chitosan-coated solid lipid nanoparticles (SLN) was successfully formulated to treat HeLa cervical carcinoma. The formulation nanoparticles were nanosized and exhibited a controlled release of …
Chitosan Nanolayered Cisplatin-Loaded Lipid Nanoparticles for …
2016年11月25日 · In this study, cisplatin (CDDP)-loaded chitosan-coated solid lipid nanoparticles (SLN) was successfully formulated to treat HeLa cervical carcinoma. The formulation nanoparticles were nanosized and exhibited a controlled release of …
载有顺铂的固体脂质纳米颗粒的制备，表征和体内分布。,Die …
采用乳化分散-超声法制备载有顺铂的固体脂质纳米粒（sln）。将传统的抗肿瘤药物顺铂（cddp）掺入sln中，以获得靶向性和毒性较小的药物递送系统。cddp-sln在透射电子显微镜（tem）摄影中呈球形且均匀。平均粒径和ζ电位分别为121 +/- 15nm和-46.4 +/- 10.3mv。
顺铂固体脂质纳米粒的制备及其在大鼠体内的分布-【维普期刊官网 …
摘要 目的制备顺铂固体脂质纳米粒(CDDP-SLN),并考察其在大鼠体内的分布情况。方法采用乳化分散-超声法制备顺铂SLN,以包封率和外观为评价指标,进行正交实验筛选最优处方,并考察其形态、粒径和zeta电位。
Preparation, characterization and in vivo distribution of solid l ...
An emulsification dispersion-ultrasonication method was employed to prepare solid lipid nanoparticles (SLN) loaded with cisplatin. The conventional antitumor drug cisplatin (CDDP) was incorporated into SLN to obtain a targeted and less toxic drug delivery system.
Chitosan Nanolayered Cisplatin-Loaded Lipid Nanoparticles for ... - PubMed
In this study, cisplatin (CDDP)-loaded chitosan-coated solid lipid nanoparticles (SLN) was successfully formulated to treat HeLa cervical carcinoma. The formulation nanoparticles were nanosized and exhibited a controlled release of drug in physiological conditions.
Preparation, characterization and in vivo distribution of solid lipid ...
An emulsification dispersion-ultrasonication method was employed to prepare solid lipid nanoparticles (SLN) loaded with cisplatin. The conventional antitumor drug cisplatin (CDDP) was incorporated into SLN to obtain a targeted and less toxic drug delivery system. The CDDP-SLNs were spherical and uni …
<br>通过 TAT 靶向固体脂质纳米颗粒共同递送紫杉醇和 TOS-顺 …
目的本研究的目的是开发反式激活转录激活剂（tat）修饰的固体脂质纳米颗粒（sln），用于共同递送紫杉醇（ptx）和α-生育酚琥珀酸酯-顺铂前药（tos-cddp）（tat ptx） /tos-cddp slns）以实现针对宫颈癌的协同抗肿瘤活性。
壳聚糖纳米级顺铂脂质纳米颗粒在宫颈癌中增强抗癌功 效 …
在这项研究中，顺铂（cddp）负载的壳聚糖包衣的固体脂质纳米颗粒（sln）已成功配制以治疗hela宫颈癌。 制剂纳米颗粒是纳米尺寸的，并且在生理条件下表现出药物的受控释放。
(PDF) Chitosan Nanolayered Cisplatin-Loaded Lipid Nanoparticles …
2016年12月1日 · In this study, cisplatin (CDDP)-loaded chitosan-coated solid lipid nanoparticles (SLN) was successfully formulated to treat HeLa cervical carcinoma. The formulation nanoparticles were nanosized...