Dopamine beta-hydroxylase - Wikipedia
Dopamine beta-hydroxylase (DBH), also known as dopamine beta-monooxygenase, is an enzyme (EC 1.14.17.1) that in humans is encoded by the DBH gene. Dopamine beta-hydroxylase catalyzes the conversion of dopamine to norepinephrine. The three substrates of the enzyme are dopamine, vitamin C (ascorbate), and O 2.
Dopamine Beta Hydroxylase - an overview | ScienceDirect Topics
Dopamine beta-hydroxylase (DBH) is a copper-containing mono-oxygenase that converts dopamine to norepinephrine in noradrenergic neurons, adrenergic neurons, and adrenal chromaffin cells. Therefore, DBH controls both norepinephrine synthesis and the dopamine/norepinephrine ratio in noradrenergic cells.
多巴胺β羟化酶 - 维基百科，自由的百科全书
多巴胺β羟化酶 （英語： Dopamine β-hydroxylase ，简称DBH）是一种多巴胺转化为去甲肾上腺素的酶。 Dopamine is converted to norepinephrine by the enzyme dopamine β-hydroxylase.
Dopamine Beta-Hydroxylase Deficiency - GeneReviews® - NCBI Bookshelf
2003年9月4日 · Dopamine beta-hydroxylase (DBH) deficiency is characterized by lack of sympathetic noradrenergic function resulting in profound deficits in autonomic regulation of cardiovascular function (orthostatic hypotension) and other autonomic dysfunction (ptosis, nasal stuffiness, sleep difficulties, and impaired ejaculation in males).
Dopamine Beta Hydroxylase: Key Enzyme Insights
2024年8月22日 · Dopamine beta hydroxylase, also known as dopamine β-hydroxylase, is a copper-containing enzyme that catalyzes the conversion of dopamine to norepinephrine, two essential neurotransmitters in the central and peripheral nervous systems.
Dopamine beta‐hydroxylase and its genetic variants in human health …
Dopamine beta-hydroxylase (DβH, dopamine β-monooxygenase; EC 1.14.17.1) is an enzyme required to synthesize NE from dopamine (DA) in noradrenergic cells of the locus coeruleus (LC) and post-ganglionic sympathetic fibers, as well as in adrenal medulla chromaffin cells and epinephrine neurons (Park et al. 1976; O'Connor et al. 1979; Duong et al ...
Dopamine beta-hydroxylase and its genetic variants in human ... - PubMed
Dopamine beta-hydroxylase (DβH) is an essential neurotransmitter-synthesizing enzyme that catalyzes the formation of norepinephrine (NE) from dopamine and has been extensively studied since its discovery in the 1950s.
多巴胺β-羟化酶及其在人类健康和疾病中的遗传变异。,Journal of …
2019年10月31日 · Dopamine beta-hydroxylase (DβH) is an essential neurotransmitter-synthesizing enzyme that catalyzes the formation of norepinephrine (NE) from dopamine and has been extensively studied since its discovery in the 1950s.
DBH dopamine beta-hydroxylase [ Homo sapiens (human) ]
2024年12月10日 · The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter …
DBH Gene - Dopamine Beta-Hydroxylase
2024年12月9日 · DBH (Dopamine Beta-Hydroxylase) is a Protein Coding gene. Diseases associated with DBH include Orthostatic Hypotension 1 and Dopamine Beta-Hydroxylase Deficiency. Among its related pathways are Biogenic amine synthesis and Metabolism. Gene Ontology (GO) annotations related to this gene include copper ion binding and L …
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