Fetuin - Wikipedia
Like fetuin-A, fetuin-B is made predominantly by the liver and to a lesser extent by a number of secretory tissues. Fetuins exist in all vertebrate genomes including fish and reptiles . Fetuins are members of a family of proteins that evolved from the protein cystatin by gene duplication and exchange of gene segments.
什么是胎球蛋白A (fetuin-A)？ - 知乎
胎球蛋白A (fetuin-A)是由肝脏产生，分泌到血液中的蛋白。 它们属于介导血液中各种物质的转运和利用的结合蛋白。 人胎球蛋白也称为α2-HS糖蛋白 (AHSG)、AHS、HSGA和胎球蛋白A。
The structure, biosynthesis, and biological roles of fetuin-A: A review
2022年7月17日 · Fetuin-A, formerly known as phosphoprotein 63 KDa (pp63) or countertrypin, is a plasma carrier protein that helps to transport and make a wide range of substances available in the bloodstream.
胎球蛋白 - 百度百科
fetuin 定 义 发现于胎牛血清，两条肽链自同一前体切割产生并以一对二硫键相连，含量占总蛋白质的45%，等电点较低，含糖量达35%，有3条寡糖链(每条3.4 kDa)，由分子质量不等的糖蛋白组成。
The structure, biosynthesis, and biological roles of fetuin-A
2022年7月18日 · Fetuin-A is a heterodimeric plasma glycoprotein containing an A-chain of 282 amino acids and a B-chain of 27 amino acid residues linked by a single inter-disulfide bond. It is predominantly expressed in embryonic cells and adult hepatocytes, and to a lesser extent in adipocytes and monocytes.
Fetuin - an overview | ScienceDirect Topics
In addition to its direct effects on the insulin receptor, fetuin-A promotes insulin resistance by triggering a proinflammatory state. Fetuin-A treatment increases expression of proinflammatory cytokines, and at the same time it reduces adiponectin expression in both adipocytes and monocytes (Hennige et al., 2008).
Fetuin - an overview | ScienceDirect Topics
Fetuin-A stabilizes colloidal nanoscopic complexes with Ca and P and prevents crystal growth by shielding mechanisms. We termed the complex “calciprotein particles” because they share functional and structural similarities to lipoprotein particles like low-density lipoproteins.
Tissue chaperoning—the expanded functions of fetuin-A beyond …
Fetuin-A, a plasma chaperone protein guarding tissues from chronic damage. At first glance, the multifaceted functions of fetuin-A as systemic calcification inhibitor and a crucial factor moderating inflammation and fibrosis in tissue almost seem too much for one single protein.
Fetuin-A: a multifunctional protein - PubMed
Fetuin, first isolated from fetal bovine serum and now most commonly known as either fetuin-A, alpha-2-HS-glycoprotein (recommended name by UniprotKB and PIR), or α2-Heremans-Schmid glycoprotein, functions as an important component of diverse normal and pathological processes, including vascular calcification and bone metabolism regulation ...
胎球蛋白 | NEB
Fetuin is a glycoprotein containing sialylated N-linked and O-linked glycans that can be used as a positive control for endoglycosidase enzymes that cleave both N-linked and O-linked carbohydrates. Purified from fetal calf serum for simplified analysis