NF-κB - Wikipedia
网页In turn, mRNA is translated into protein, resulting in a change of cell function. [ 2 ][ 3 ][ 4 ][ 5 ] Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival.
NF-κB - 百度百科
网页核因子κB（nuclear factor kappa-B，NF-κB）蛋白最早由David Baltimore发现，该蛋白家族可以选择性的结合在B 细胞 κ- 轻链 增强子 上调控许多基因的表达。. 在几乎所有的 动物细胞 中都能发现NF-κB，它们参与细胞对外界刺激的响应，如 细胞因子 、 辐射 、重金属、 病毒 ...
NFkB 通路 | Cell Signaling Technology
网页核因子-κB (NF-κB)/Rel 蛋白包括 NF-κB2 p52/p100、NF-κB1 p50/p105、c-Rel、RelA/p65 和 RelB。. 这些蛋白起到二聚化转录因子的作用，可调节基因表达，并可影响到各种不同的生物学过程，包括先天和适应性免疫、炎症、应激反应、B 细胞发育和淋巴器官形成。. 在经 …
NF-κB signaling in inflammation | Signal Transduction and
网页2017年7月14日 · NF-κB target inflammation not only directly by increasing the production of inflammatory cytokines, chemokines and adhesion molecules, but also regulating the cell proliferation, apoptosis ...
快速了解NF-κB 通路 - 知乎 - 知乎专栏
网页NF-κB（Nuclear Factor kappa-light-chain-enhancer of activated B cells）通路是一种在细胞信号传递中极为重要的途径，它在 调控免疫反应、炎症反应、细胞生长与死亡 等多种生理过程中起着关键作用。. 这一通路能….
NF-κB in biology and targeted therapy: new insights and ... - Nature
网页2024年3月4日 · Initially, NF-κB signaling was identified as a pivotal pathway in mediating inflammatory responses. However, with extensive and in-depth investigations, researchers have discovered that its role...
The nuclear signaling of NF-κB: current knowledge, new ... - Nature
网页2009年12月8日 · The nuclear factor-kappa B (NF-κB) transcription factor plays a critical role in diverse cellular processes associated with proliferation, cell death, development, as well as...
NF-kappaB Signaling Pathways in Neurological Inflammation: A …
网页2015年12月18日 · The NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) transcription factor family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism for the cells in response to a …
NFkappaB is a Key Player in the Crosstalk between Inflammation …
网页2019年3月30日 · NFκB is a ubiquitous transcription factor involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens [ 73, 74, 75, 76, 77 ]. The family of NFκB proteins includes p52/p100, p50/p105, c-Rel, RelA/p65, and RelB.
NF-kappaB signaling pathway and its therapeutic implications in …
网页The nuclear factor-kappaB (NF-kappaB) pathway is one of the most important cellular signal transduction pathways involved in both physiologic processes and disease conditions. It plays important roles in the control of immune function, inflammation, stress response, differentiation, apoptosis, and cell survival.
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