Perphenazine | C21H26ClN3OS | CID 4748 - PubChem
Perphenazine is 10 to 15 times as potent as chlorpromazine; that means perphenazine is a highly potent antipsychotic. In equivalent doses it has approximately the same frequency and severity of early and late extrapypramidal side-effects compared to Haloperidol .
Perphenazine - Wikipedia
Perphenazine is a typical antipsychotic drug. Chemically, it is classified as a piperazinyl phenothiazine. Originally marketed in the United States as Trilafon, it has been in clinical use for decades.
Perphenazine - NIST Chemistry WebBook
2020年2月5日 · Formula: C 21 H 26 ClN 3 OS Molecular weight : 403.969 IUPAC Standard InChI: InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 Copy
Perphenazine Tablets (Perphenazine): Side Effects, Uses, Dosage ...
Its structural formula is: Perphenazine (perphenazine) has actions at all levels of the central nervous system, particularly the hypothalamus. However, the site and mechanism of action of therapeutic effect are not known. Perphenazine is indicated for use in the treatment of schizophrenia and for the control of severe nausea and vomiting in adults.
Perphenazine | The Merck Index Online
2020年2月5日 · Perphenazine UNII FTA7XXY4EZ Molecular formula C 21 H 26 ClN 3 OS Molecular weight 403.97 Percent composition C 62.44%, H 6.49%, Cl 8.78%, N 10.40%, O 3.96%, S 7.94% Standard InChI InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 Standard InChIKey RGCVKNLCSQQDEP ...
Perphenazine Tablets, USP DESCRIPTION: Perphenazine (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-pipera-zineethanol), a piperazinyl phenothiazine, having the chemical formula, C21H26CIN3OS. It is...
PERPHENAZINE | 58-39-9 - ChemicalBook
Perphenazine (58-39-9) is a clinically useful typical antipsychotic drug. The therapeutic mode of action is not well understood but it binds to a wide variety of receptors including serotonin, histamine, dopamine, and α-adrenergic.1 Perphenazine is an inhibitor of acid sphingomyelinase(ASM)2 and positively affected xenografted tumor growth via ...
Perphenazine | CAS#:58-39-9 | Chemsrc - 化源网
2024年1月2日 · Perphenazine is a typical antipsychotic drug, inhibits 5-HT2Areceptor, Alpha-1A adrenergic receptor, Dopamine receptor D2/D3, D2L receptor, and Histamine H1 receptor, with Ki values of 5.6, 10, 0.765/0.13, 3.4, and 8 nM, respectively. [1]. Richtand NM, et al. Dopamine and serotonin receptor binding and antipsychotic efficacy.
Perphenazine: Package Insert / Prescribing Info - Drugs.com
2024年12月16日 · Perphenazine (4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol), a piperazinyl phenothiazine, having the chemical formula, C 21 H 26 CIN 3 OS. It is available as oral tablets containing 2 mg, 4 mg, 8 mg, and 16 mg of perphenazine.
Perphenazine USP Reference Standard CAS 58-39-9 Sigma-Aldrich
Empirical Formula (Hill Notation): C 21 H 26 ClN 3 OS. CAS Number: 58-39-9. Molecular Weight: 403.97. MDL number: MFCD00056798. UNSPSC Code: 41116107. PubChem Substance ID: 329750721. NACRES: ... Perphenazine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP ...