Rhabdomyosarcoma With Diffuse Bone Marrow Metastases
We present a case of rhabdomyosarcoma with this unique pattern of bone marrow metastases in which initial differential diagnosis favored a leukemic picture. This paper will go over the diagnostic techniques utilized throughout our patient’s disease course as well as treatment.
Pediatric rhabdomyosarcoma with bone marrow metastasis
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of adolescence and childhood. Although most patients with localized RMS are cured, outcome of those with metastatic disease remains unsatisfactory. RMS with bone marrow (BM) metastasis accounts for approximately 6% of all cases with RMS and has a 3-year event-free survival of 14%.
Bone Marrow Involvement of Rhabdomyosarcoma from Unknown …
2014年6月10日 · The bone marrow aspirate smear showed immature cells with vacuole and blue cytoplasm; these immature cells were considered as metastasis of a solid tumor (Figure 1). Excisional biopsy of the axillary lymphadenopathy was performed and the histopathological diagnosis was the alveolar type of rhabdomyosarcoma (RMS).
Rhabdomyosarcoma with bone marrow infiltration mimicking
Unusual clinical presentation of the disease with massive bone marrow infiltration at the disease onset and mimicking hematologic neoplasm is rarely seen. A case is presented of a 14-year-old, previously healthy girl hospitalized for outpatiently detected leukocyte elevation.
Successful Multi-Modal Treatment of Uterine Rhabdomyosarcoma
5 天之前 · Additional work-up included bone marrow aspirate, CT chest, and PET imaging, which were negative for metastasis. Fig. 1 Coronal images from the MRI obtained at the time of initial presentation demonstrating 9 x 13 x 19 cm mass centered on the uterus and vagina, encasing and displacing both distal ureters resulting in bilateral ...
Nasal embryonal rhabdomyosarcoma with bone marrow metastasis …
2019年4月1日 · Immunohistochemical staining in bone marrow biopsy and flow cytometry in aspirate samples may help to establish the diagnosis (CD45 negativity and CD56 positivity) and cytogenetic studies can be useful in identifying a RMS subtype.
Rhabdomyosarcoma infiltrating bone marrow - International …
2014年10月28日 · The bone marrow aspirate smears revealed a cellular marrow with infiltration by blast-like cells with large round nuclei, reticulated chromatin with multiple nucleoli, moderate amount of basophilic cytoplasm and cytoplasmic vacuolation.
Alveolar rhabdomyosarcoma with massive bone marrow …
2022年5月18日 · A computed tomography scan revealed systemic lymphadenopathy, splenomegaly, bilateral pleural effusions, and massive ascites. A bone marrow aspirate revealed massive infiltration by large abnormal cells with a basophilic cytoplasm and cytoplasmic vacuoles (Figure 1A). Flow cytometry analysis showed that the abnormal cells expressed only CD56 ...
Phagocytic rhabdomyosarcoma cells in bone marrow
2021年7月14日 · Bone marrow aspirate showed monotonous infiltrate of rhabdomyosarcoma cells with cytoplasmic vacuoles, loose chromatin nucleus (A), and intracytoplasmic phagocytosis of erythrocytes (B), leukocytes (C), platelets (D). Wright–Giemsa stain, × 1000.
Rhabdomyosarcoma infiltrating bone marrow - PubMed
We present a case of 26-year-old male, previously diagnosed as rhabdomyosarcoma (RMS) of perineal region. The peripheral smear showed a leukoerythroblastic picture with an occasional atypical cell. The bone marrow aspirate and biopsy showed monotonous sheets of …