Thromboplastin - Wikipedia
Thromboplastin acts on and accelerates the activity of Factor Xa, also known as thrombokinase, [1] aiding blood coagulation through catalyzing the conversion of prothrombin to thrombin. Thromboplastin is found in brain, lung, and other tissues and especially in blood platelets. [2]
Thromboplastin - an overview | ScienceDirect Topics
Thromboplastin. In subject area: Medicine and Dentistry. The traditional term “thromboplastin” refers to a phospholipid-protein extract of tissue (usually lung, brain, or placenta) that contains both the tissue factor and phospholipid necessary to promote activation of factor X by factor VII.
Partial Thromboplastin Time (PTT) Test - MedlinePlus
A partial thromboplastin time (PTT) test uses a blood sample to measure how long it takes for your blood to make a clot. Normally, when you get a cut or injury that causes bleeding, many different types of proteins in your blood work together to make a clot to stop the bleeding. These proteins are called coagulation factors or clotting factors.
Health products policy and standards - World Health Organization …
This test requires the use of laboratory reagents called thromboplastins which are commercial products producing different clotting times for a particular blood sample. In the past, all too often, patients going to different hospitals were given different prescriptions depending on the type of thromboplastins used by the hospital.
Guidelines for thromboplastins and plasma used to control oral ...
2013年10月30日 · The adjustments are made on the basis of the results of the prothrombin-time or a similar test on the patient’s blood. The test, which requires reagents called thromboplastins, is controlled by the use of calibrated thromboplastins and plasmas.
Oral Anticoagulant Therapy - PMC - National Center for …
2012年1月23日 · Thromboplastins vary in responsiveness to a reduction of the vitamin K-dependent coagulation factors. An unresponsive thromboplastin produces less prolongation of the PT for a given reduction in vitamin K-dependent clotting factors than a responsive one.
Thromboplastin - an overview | ScienceDirect Topics
Thromboplastin is a substance that is upregulated and released from damaged brain tissue after moderate or severe Traumatic Brain Injury (TBI). It activates procoagulant factors, leading to blood clot formation and potentially increasing the risk of cerebral infarction. AI generated definition based on: Handbook of Clinical Neurology, 2017.
Thromboplastin - Encyclopedia.com
2018年5月14日 · thromboplastin (tissue factor; Factor III) A membrane glycoprotein expressed on the surface of damaged tissue cells that initiates the cascade of reactions leading to formation of a blood clot.
Current Concepts in Anticoagulant Therapy - Mayo Clinic …
A more responsive thromboplastin produces less rapid activation of coagulation factors and results in a greater prolongation of the PT for a given reduction in clotting factors.
Thromboplastin - an overview | ScienceDirect Topics
Thromboplastins were originally tissue extracts obtained from different species and different organs containing tissue factor and phospholipid. Because of the potential hazard of viral and other infections from handling human brain, it should no …