In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid ...
网页In Conclusion, povidone-iodine nasal antiseptic solutions at concentrations as low as 0.5% rapidly inactivate SARS-CoV-2 at contact times as short as 15 seconds. Intranasal use of PVP-I has demonstrated safety at concentrations of 1.25% and below and may play an adjunctive role in mitigating viral transmission beyond personal protective ...
Can Nasal Antiseptics Help Prevent COVID-19? - Verywell Health
网页2020年10月30日 · Iodine Nasal Antiseptics. PVP-I is a betadine solution that can destroy bacteria, fungi, and viruses. It has been used against: Methicillin-Resistant Staphylococcus Aureus (MRSA) Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) Influenza H1N1. Rotavirus.
Efficacy of “Essential Iodine Drops” against Severe Acute …
网页2021年7月9日 · Intranasal saline sprays containing elemental iodine as an active ingredient has been used for nasal moisturizing and prevention and/or treatment of sinusitis or rhinitis . Iodine-containing intranasal/oral moisturizing saline sprays are being explored as drug agents against coronaviruses.
Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for …
网页An oro-nasal spray is designed to apply the PVP-I in nose and oral cavity to gain a protective layer or coating over nasal and oral mucosa, so that SARS-CoV-2 can’t bind with the ACE-2 receptor and prevent their entry inside.
A Pilot Study of 0.4% Povidone-Iodine Nasal Spray to Eradicate …
网页2022年12月21日 · This study aimed to evaluate the virucidal efficacy of 0.4% povidone-iodine (PVP-I) nasal spray against SARS-CoV-2 in the patients’ nasopharynx at 3 minutes and 4 hours after PVP-I exposure. Patients and Methods.
Efficacy of Povidone-Iodine Nasal and Oral Antiseptic ... - PubMed
网页Nasal and oral PVP-I antiseptic solutions are effective at inactivating the SARS-CoV-2 at a variety of concentrations after 60-second exposure times. The formulations tested may help to reduce the transmission of SARS-CoV-2 if used for nasal decontamination, oral decontamination, or surface decontam ….
The Effect of Povidone-Iodine Nasal Spray on Nasopharyngeal …
网页2021年11月2日 · The 2.0% PVP-I group showed statistically significant improvement in all symptom categories; however, it also reported a high rate of nasal burning. Olfaction via UPSIT showed improvement by at least one category in all groups.
The Effect of Povidone‐Iodine Nasal Spray on Nasopharyngeal …
网页2021年11月1日 · In this randomized, triple-blinded, placebo-controlled clinical trial, we compared topical nasal saline to low and high concentration PVP-I as potential therapies in COVID-19 patients. We found that saline and low dose (0.5%) PVP-I nasal sprays are overall well-tolerated, though more nasal burning symptoms were reported in the 2.0% PVP-I …
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce ...
网页Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19 A Randomized Clinical Trial. Jeremy Guenezan, MD 1; Magali Garcia, MD, PhD 2; Deidre Strasters, MD 1; et al Clément Jousselin, PhD 2; Nicolas Lévêque, PharmD, PhD 2; Denis Frasca, MD, PhD 3; Olivier Mimoz, MD, PhD 1.
Povidone-Iodine Use in Sinonasal and Oral Cavities: A Review of …
网页2020年6月10日 · Approaches to nasal and oral decontamination with povidone-iodine (PVP-I) have been published to reduce nosocomial spread of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2). The safety of PVP-I topically applied to the nasal and oral cavity is addressed by a literature review.