Nidogen-1 - Wikipedia
网页Nidogen-1 ( NID-1 ), formerly known as entactin, is a protein that in humans is encoded by the NID1 gene. [ 5][ 6] Both nidogen-1 and nidogen-2 are essential components of the basement membrane alongside other components such as type IV collagen, proteoglycans (heparan sulfate and glycosaminoglycans ), laminin [ 7] and fibronectin.
Entactin: structure and function - PubMed
网页Entactin is an integral and ubiquitous component of the basement membrane. The amino acid sequences of the mouse and human molecules have been determined and exhibit 85% sequence identity. The molecule is organized into three structural domains, an N-terminal globule (I) is linked to a smaller C-terminal globule (III) by a rigid stalk (II ...
Nidogen in development and disease - PubMed
网页2024年3月14日 · Nidogen, also known as entactin, is a multifunctional glycoprotein that plays a crucial role in the maintenance of the basement membrane (BM), morphogenesis and neuronal plasticity. This review aims to provide an overview of the structural features, molecular interactions and diverse functions associated with Nidogen.
Entactin - an overview | ScienceDirect Topics
网页Entactin, also known as nidogen, is a sulfated glycoprotein that is an essential component of basement membranes. It forms a tight complex with laminin and plays a role in cell attachment and tissue assembly.
Entactin: Structure and Function | American Journal of Respiratory …
网页1990年6月18日 · Entactin is an integral and ubiquitous component of the basement membrane. The amino acid sequences of the mouse and human molecules have been determined and exhibit 85% sequence identity. The molecule is organized into three structural domains, an N-terminal globule (I) is linked to a smaller C-terminal globule (III) by a rigid stalk (II ...
层粘连蛋白 - 维基百科，自由的百科全书
网页层粘连蛋白 （英語： laminin）是 细胞外基质 的高 分子量 （~400至~900kDa） 糖蛋白。. 它们是 基底层 （基底膜 的一层）的主要成分，是大多数细胞和器官的一个蛋白质网络基础。. 层粘连蛋白是基底层的重要和生物活性部分，影响细胞分化，迁移和黏附 [1][2 ...
Nidogen in development and disease - Frontiers
网页2024年3月13日 · Nidogen, also known as entactin, is a multifunctional glycoprotein that plays a crucial role in the maintenance of the basement membrane (BM), morphogenesis and neuronal plasticity. This review aims to provide an overview of the structural features, molecular interactions and diverse functions associated with Nidogen.
Amino acid sequence and domain structure of entactin.
网页1988年12月12日 · Entactin (nidogen), a 150-kD sulfated glycoprotein, is a major component of basement membranes and forms a highly stable noncovalent complex with laminin. The complete amino acid sequence of mouse entactin has been derived from sequencing of …
Entactin - an overview | ScienceDirect Topics
网页Entactin is a 170-kDa sulfated glycoprotein that binds LN and collagen IV. A family of LN-binding proteins ranging from 67 to 100 kDa have also been identified; however, these have not been well characterized as to form and function.
Biological functions of entactin - ScienceDirect
网页1993年1月1日 · Entactin is a sulfated multidomain glycoprotein component of basement membranes. The molecule consists of 1217 amino acids which are organized into two terminal globular domains linked by a rod-like structure largely composed of four EGF- and one thyroglobulin-like cysteine-rich homology repeats.