Polycomponent mesotherapy formulations for the treatment of …
2015年4月7日 · The quintessential example of a polycomponent formulation - NCTF(®) (New Cellular Treatment Factor) - includes vitamins, minerals, amino acids, nucleotides, coenzymes and antioxidants, as well as hyaluronic acid, designed to help fibroblasts function more efficiently by providing a more optimal environment for biochemical processes and energy ...
Polycomponent mesotherapy formulations for the treatment …
Polycomponent mesotherapy solutions, such as NCTF, have been widely and successfully employed for many years as treatments for skin aging. Although the composition of these formulations may appear daunting at first, a consideration of the physiological effects of the individual components can help to demystify these complex therapies.
Evaluation of the Effectiveness of an Innovative Polycomponent ...
2023年8月28日 · Our results show the ability of K formulation to induce a dose- and time-dependent increase in the TGF-β1 secretion relative to the controls in both models. Our findings support the notion that this polycomponent formulation could efficiently activate TGF-β1 signaling in fibroblasts, significantly synthesizing collagen I.
Efficacy of an Innovative Poly-Component Formulation in …
Our recent data on the ability of an innovative poly-component formulation (KARISMA Rh Collagen ® FACE: K formulation) to suppress the biomolecular events associated with oxidative stress-induced aging prompted us to deepen the mechanisms underlying the observed effects on aged human dermal fibroblasts (HDFs).
New Regenerative and Anti-Aging Medicine Approach Based on …
This new polycomponent formulation effectively stimulates skin regeneration, improving skin quality and texture, with significant aesthetic benefits perceived by patients, and a low incidence of adverse events, marking a promising advancement in regenerative medicine.
Evaluation of the Effectiveness of an Innovative Polycomponent ...
2023年8月28日 · The recent availability on the market of an innovative polycomponent formulation (KARISMA Rh Collagen ® FACE, K) containing noncrosslinked high-molecular-weight hyaluronic acid (HMW-HA), a human recombinant polypeptide of collagen-1 alpha chain, and carboxymethyl cellulose (CMC), attracted our scientific interest in evaluating its biomolecular ...
Evaluation of the Effectiveness of an Innovative Polycomponent ...
2023年8月28日 · The recent availability on the market of an innovative polycomponent formulation (KARISMA Rh Collagen® FACE, K) containing noncrosslinked high-molecular-weight hyaluronic acid (HMW-HA), a human...
Minimally invasive mesotherapy using a new polycomponent formulation can improve the clinical appearance of facial skin. However, a larger-scale and well-controlled investigation of the clinical...
The rationale for developing complex polycomponent mesopreparations is based on the principle that aging skin needs to be supplied with the various substrates that are key to the adequate functioning of the fibroblast. The quintessential example of a polycomponent formulation – NCTF® (New Cellular Treatment Factor) – includes vitamins,
Evaluation of the Effectiveness of an Innovative Polycomponent ...
Our findings support the notion that this polycomponent formulation could efficiently activate TGF-β1 signaling in fibroblasts, significantly synthesizing collagen I. To the best of our knowledge, this is the first study showing in vitro the biological effects of a polycomponent formulation of non-crosslinked HMW-HA, recombinant polypeptide of ...