Thiadiazoles - Wikipedia
In chemistry, thiadiazoles are a sub-family of azole compounds, with the name thiadiazole originating from the Hantzsch–Widman nomenclature. Structurally, they are five-membered heterocyclic compounds containing one sulfur and two nitrogen atoms.
1,3,4-Thiadiazoles: A potent multi targeted ... - ScienceDirect
2015年3月6日 · Despite a significant work on thiadiazoles, continuous efforts are still being made to identify novel heterocyclic compounds with potent biological activities. This review may help the medicinal chemists to develop new leads possessing 1,3,4-thiadiazole nucleus with higher efficacy and reduced side effects.
1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in …
2014年4月9日 · An efficient eco-friendly, simple, and green synthesis of some new spiro-N-(4-sulfamoyl-phenyl)-1,3,4-thiadiazole-2-carboxamide derivatives as potential inhibitors of SARS-CoV-2 proteases: drug-likeness, pharmacophore, molecular docking, and DFT exploration.
1,3,4‐Thiadiazole and its Derivatives: A Review on Recent …
2013年3月1日 · Thiadiazole is a 5-membered ring system containing hydrogen-binding domain, sulfur atom, and two-electron donor nitrogen system that exhibit a wide variety of biological activity. They occur in four isomeric forms in the nature viz. 1,2,3-thiadiazole; 1,2,5-thiadiazole; 1,2,4-thiadiazole; and 1,3,4-thiadiazole (Scheme 1). Thiadiazole structures.
Synthesis and Evaluation of Antimicrobial Activity of 1, 3, 4 ...
The literature survey revealed that Thiadiazole moiety is an imperative heterocyclic system with different and diverse biological activities. Therefore, the objective was to prepare different Thiadiazole derivatives and evaluate them for their antimicrobial, analgesic, antioxidant, anti-inflammatory and antihelmintic.
Thiadiazoles - an overview | ScienceDirect Topics
2012年5月20日 · Thiadiazole is a heterocyclic moiety consisting of one sulfur and two nitrogen atoms (Fig. 41). A current literature survey unleashed that among thiadiazoles, 1,3,4-thiadiazole moiety has been frequently taken up by the researcher to explore its biological activity.
Synthetic Methods, Chemistry, and the Anticonvulsant Activity of ...
Thiadiazole is a versatile moiety that exhibits a wide variety of biological activities. Thiadiazole moiety acts as “hydrogen binding domain” and “two-electron donor system.” It also acts as a constrained pharmacophore.
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噻二唑，是一种 化学物质，外观呈白色结晶性粉末，其分子式为C3H4N2S2。 熔点183-187℃。 溶于热水、甲醇、乙醇和N，N- 二甲基甲酰胺. 1.不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 2.戴适当的手套和护目镜或面具。 刺激眼睛、呼吸系统和皮肤。
Thiadiazole - an overview | ScienceDirect Topics
2010年4月29日 · Thiadiazole is defined as a type of heterocyclic compound belonging to the azole class, consisting of two carbon atoms, two nitrogen atoms, and one sulfur atom in its ring structure. It is used in drug molecules and as a bioisostere for the development of analogs with enhanced biological properties.
1,3,4-Thiadiazole | C2H2N2S | CID 119391 - PubChem
1,3,4-Thiadiazole | C2H2N2S | CID 119391 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.